High molecular weight cytokeratins
WebNevertheless, the expression of high molecular weight cytokeratin tended to correlate with the expression of low molecular weight cytokeratin( = 0.0929 , = 0.2354 ;Spearmantest). . . Considerable Overlapping of Cytokeratins Was Evidenced in NSCLC but Not in SCLC. Web34βE12. 34βE12, often written as 34betaE12 and also known as CK34βE12 and keratin 903 ( CK903 ), is an antibody specific for high molecular weight cytokeratins 1, 5, 10 and 14. [1] [2] It is sometimes, less precisely, referred to as high-molecular weight keratin ( HMWK) and high-molecular weight cytokeratin ( HMWCK ).
High molecular weight cytokeratins
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WebCytokeratin, High Molecular Weight (Concentrate) Clone 34βE12 Reacts with the 68 kDa, 58 kDa, 56.5 kDa and 50 kDa proteins corresponding to cytokeratins 1, 5, 10 and 14. The antibody labels squamous, ductal and complex epithelia. WebCocktail of a high- and a low-molecular-weight monoclonal cytokeratin antibody • Expressed in the epidermis and adnexal epithelium • Stains all epithelial tumors (squamous cell …
WebThe cytokeratins are the largest and most complex group of intermediate filaments and include a family of at least 30 proteins with molecular weights ranging from 40 to 68 kD. … WebNov 12, 2010 · Histologically, the majority of basal-like breast cancers is of IDC-NST type, high histological grade, and characterized by exceptionally high mitotic indices, the presence of central necrotic or ...
WebOct 19, 2004 · DDC feeding of these mice resulted in a markedly higher toxicity in K8 knock-out than in K18 knock-out or wild-type mice. Furthermore, no MBs were formed in the K8 knock-out mice, whereas K18 knock-out mice revealed even spontaneous MB formation at high age 16, 73. These studies demonstrated that K8, but not K18, is essential for MB … WebDec 1, 2000 · The antigenicity of high-molecular-weight cytokeratins could be restored using microwave retrieval in an acidic buffer. Although the exact mechanism concerning microwave antigen retrieval is not clear, it is possible that this technique restores antigenicity by unfolding of keratin or an interacting protein.13 Recently, ...
WebMay 5, 2005 · It was recognized by many groups that the high-molecular-weight cytokeratins CK5 and CK14, which form in vivo complexes, are expressed in the basal …
WebHematoxylin and eosin (H&E) staining is a well-established technique in histopathology. However, immunohistochemistry (IHC) interpretation is done exclusively with hematoxylin counterstaining. Our goal was to investigate the potential of H&E phineas and ferb hd wallpaperWebBecause few breast carcinomas express p63 or high-molecular-weight cytokeratins (HMW CK), the immunoreactivity values of the subpopulations of luminal epithelial cells for p63, high-molecular-weight cytokeratin 34E12, and cytokeratin 5/6 were consistent with a tumor of sweat duct origin. tsn sports australian openWebEwing sarcoma/primitive neuroectodermal tumor (ES/PNET) has recently been shown to frequently express cytokeratins, suggesting partial epithelial differentiation. Older ultrastructural studies have documented primitive cell–cell junctions in ES/PNET, reportedly resembling poorly formed desmosomes. Recently, paraffin-reactive antibodies have … tsn sports anchorsWebJun 25, 2024 · Over 25 subtypes are defined based on molecular weight (40 to 68 kDa) and isoelectric pH (5 to 8) Moll catalog number ( Cell 1982;31:11) ranges from 1 (highest … phineas and ferb headscratchersWebThe distribution of tissue polypeptide antigen (40 kD molecular weight) in normal adult and fetal liver, and in liver disease was investigated and compared with the distribution of low and high molecular weight cytokeratins. In normal liver tissue polypeptide antigen was found only in bile duct epithelium; this distribution is similar to that of high molecular … phineas and ferb heartstrings to heroWebImmunohistochemical expression of myoepithelial markers in adenomyoepithelioma of the breast：a unique paradoxical staining pattern of high-molecular weight cytokeratins [J]. Virchows Arch ， 2015 ， 466 ( 2 ): 191 - 198 . phineas and ferb heck of a dayWebMar 1, 2013 · The pan cytokeratin AE1/AE3 is a cocktail of antibodies that recognizes a wide range of cytokeratins of different molecular weights. It is very useful for identifying epithelial tumors, classifying these by degree of differentiation, and detecting micrometastases. tsn scotties tournament of hearts 2023