Hemi-protonated
WebDue to an acidic environment, this is achieved by hemi-protonated cytosines which mimick an ordinary C-G binding as it is present in double helix DNA. Hence it becomes clear that these structures are only occurring at slightly acidic to neutral conditions resulting in pH values from 4.8 to 7.0 [1, 2, 6]. I-motifs show a remarkable sta- WebCytosine-rich DNA regions can form four-stranded structures based on hemi-protonated C.C+ pairs, called i-motifs (iMs). Using CD, UV absorption, NMR spectroscopy, and DSC calorimetry, we show...
Hemi-protonated
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Web23 dec. 2024 · I-Motif is a tetrameric cytosine-rich DNA structure with hemi-protonated cytosine: cytosine base pairs. Recent evidence showed that i-motif structures in human … Web8 mei 2024 · Abstract. Here, we have explored the light-up property of coumarin 343 (C343) selectively towards various i-motif DNAs based on the recognition of hemi-protonated …
Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 Webhemiprotonated ( not comparable ) protonated at only half of the possible sites (typically, 1 of 2) quotations . This page was last edited on 29 September 2024, at …
Web2 dec. 2024 · Abstract I-motifs are non-canonical nucleic acids structures characterized by intercalated H-bonds between hemi-protonated cytosines. Evidence on the involvement … WebA possible scheme for non-enzymatic RNA replication at pH 4-5. (a) tRNAGly (GCC) forms dimers through its GCC anticodon due to hemi-protonation of the central cytosine at pH 4-5 [37] (b) At pH...
Web31 jan. 2024 · i-Motifs are four-stranded DNA structures formed from sequences rich in cytosine, held together by hemi-protonated cytosine-cytosine base pairs. These structures have been utilized extensively as pH-switches in DNA-based nanotechnology. Recently there has been an increasing interest in i-motif struc …
Web1 jun. 2024 · i-Motifs are quadruplex DNA structures formed from sequences rich in cytosine and held together by intercalated, hemi-protonated cytosine–cytosine base pairs. These sequences are prevalent in gene promoter regions and may play a role in gene transcription. tire inglesWeb5 nov. 2024 · Specifically, we have studied the excited-state dynamics for both neutral and hemi-protonated cytosine chains (dC) 10. The latter assembles into a so-called i-motif structure. tire inflator tools professionalWeb22 dec. 1994 · At slightly acid or even neutral pH, oligodeoxynucleotides that include a stretch of cytidines form a tetramer structure in which two parallel-stranded duplexes have their hemi-protonated C.C+ base pairs face-to-face and fully intercalated, in a so-called i-motif, first observed serendipitously in [d(TC5)]4. tire inflator with battery chargerWebIt would therefore appear possible that, as illustrated in Figure 5b, hemi- protonated linear GCC repeat sequences could serve as templates to produce identical copies at pH 4-5. tire inflator valve connectorWeb20 jan. 2012 · We have proposed mechanisms for two key RNA world activities that are compatible with an acidic milieu: (i) non-enzymatic RNA replication of a hemi-protonated cytosine-rich oligonucleotide, and (ii) specific aminoacylation of tRNA/hairpins through triple helix interactions between the helical aminoacyl stem and a single-stranded … tire inflator with jump starterWebi-Motif (the name stems from “intercalated”), also known as i-DNA, is a pH-dependent four-stranded nucleic acid structure formed by cytosine-rich sequences via hemi-protonated and intercalated C C+base pairs. tire inflators at lowe\u0027sWeb22 dec. 1994 · PubMed Abstract: At slightly acid or even neutral pH, oligodeoxynucleotides that include a stretch of cytidines form a tetramer structure in which two parallel-stranded … tire inside edge scalloping